Although deconstructionism forces us to concede that any "slant" in XKCD is merely a textual artifact, and all critical perspectives on the work are equally valid, it is nevertheless more equally valid to conclude that XKCD's gender politics may be more self-serving to the author than a legitimate (pace manocentric male-ocratic words like "legitimate") statement of empathy or outrage over the station of the modern woman in today's technological world.
(Taking this comment seriously...) After spending time with Randall IRL, I'm convinced his feelings on the subject are genuinely empathetic.
That said, I don't think the comics are a particularly good expression of this. The male is always being rational-logical and the female intuitive-wholistic, which seems a bit sexist, even if the rational-logical character is always the butt of the joke.
