I'm not sure if you're familiar with these types of experiences. The entire point is that it permanently changes your outlook (for the better) after only a few uses, give or take per person. Not to get all stereotypical answer, but Steve Jobs attributes a single trip to the vision he maintained for the rest of his life.

And even if that were the case, what's the difference between taking a dose of LSD every three months and taking an over-the-counter every single day for the rest of your life, particularly when -- as with the recent case with Wellbutrin XL -- the FDA is approving things that do more harm than good because they're literally not doing any research on them?