Keeping things simple and calculating the axle weight to the fourth powers of both vehicles, the F-150 causes 5.4x the road wear of the Honda Accord while using only 1.6x the gas.
The reason this doesn't matter so much, though, is that the types of trucks used for shipping goods, when loaded, cause on the order of 10^4 the road wear, dwarfing any differences between standard commuter vehicles, which is why commercial trucks have to stop at weigh stations.
The big trucks also have a lot more tires / tire surface area, to mitigate that. IIUC, the weigh stations are to ensure they aren’t overloading the truck, so that road wear is comparable instead of being that vastly greater