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If you weld 2 sticks of metal together end to end, then bash them on the ground, they're likely to break at the weld. Insert additional physical examples here.

Likewise DNA is likely to break (and fail to be corrected) at particular points. Some of those points cause cancer, but there's only a finite set of those points since DNA is largely identical across all humans. Additionally, even if the failure is slightly to one side of the expected break, it usually shows the same symptom.



> If you weld 2 sticks of metal together end to end, then bash them on the ground, they're likely to break at the weld

This doesn't sound even remotely true to me, except in the case of an absolute beginner doing the welding




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