"While urethane can be an outstanding protective material for products such as items as small as wire or cases to items as large as residential homes, it can also be a very dangerous material. It is a recognized carcinogen, and it is hazardous to developing fetuses. Additionally, it is suspected to be toxic to the gastrointestinal system, liver, kidney, skin, and respiratory tract. It is, however, easy to prevent these dangers by wearing protective clothing and providing appropriate exhaust ventilation. It is also necessary to wash thoroughly after exposure. The risk of getting ill from urethane exposure is higher for industrial workers than residents of a community where urethane is processed, however if proper precautions are taken, adverse effects can be avoided."

https://www.thomasnet.com/articles/plastics-rubber/about-mol....