Start talking to people in the area you are interested in. Find the person is initiating the hiring process (not HR.) Find out what the need is and if you can fulfill that need. A resume should come towards the end of the interviewing process when a job has been extended. The resume is a marketing document, like a relevant piece of marketing material that a competent sales person will leave with a prospect after the prospect has agreed to make a commitment. A resume should never (general case) lead the discussion of employment.