A defined ergonomically equipped workspace that isn't in the way of other day-to-day living (with or without a door depending upon who else is regularly in the space day-to-day) and a good audio-video setup for video calls and other video recording. Even though in practice I often work elsewhere in my house on a laptop for various reasons, it's important to me to have an office.

And, as others have said, childcare and other arrangements to allow you to work without distraction.