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I think it's possible and more likely so in a niche specific to developing countries like Malaria/HIV software, low-bandwith solutions, etc.

Otherwise it's much easier to produce a 37signals, just like everywhere else, I guess.

Disclaimer: I'm an African in Africa. In my day-job, I work for a non-profit developing a Rails application for managing delivery for HIV medication (baobabhealth.org)



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